Wolfgang H Oertel Selected Research

Pramipexole (Mirapex)

7/2014	Influence of the nonergot dopamine agonist piribedil on vigilance in patients With Parkinson Disease and excessive daytime sleepiness (PiViCog-PD): an 11-week randomized comparison trial against pramipexole and ropinirole.
10/2013	Effect of long-term treatment with pramipexole or levodopa on presynaptic markers assessed by longitudinal [123I]FP-CIT SPECT and histochemistry.
1/2008	Cost effectiveness of pharmacotherapies in early Parkinson's disease.
6/2007	Efficacy of pramipexole and transdermal rotigotine in advanced Parkinson's disease: a double-blind, double-dummy, randomised controlled trial.
1/2007	Efficacy of pramipexole in restless legs syndrome: a six-week, multicenter, randomized, double-blind study (effect-RLS study).
9/2006	Controlled withdrawal of pramipexole after 6 months of open-label treatment in patients with restless legs syndrome.
9/2005	Pramipexole in the treatment of Parkinson's disease: new developments.
5/2005	Long-term efficacy and safety of pramipexole in advanced Parkinson's disease: results from a European multicenter trial.
1/2004	Low-dose pramipexole in the management of restless legs syndrome. An open label trial.

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Wolfgang H Oertel Research Topics

Disease

85	Parkinson Disease (Parkinson's Disease) 12/2023 - 01/2002
18	Restless Legs Syndrome (Restless Legs) 01/2016 - 01/2004
11	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2023 - 08/2005
9	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 12/2023 - 05/2002
9	Dementia (Dementias) 12/2023 - 01/2010
9	REM Sleep Behavior Disorder 01/2022 - 03/2008
9	Disease Progression 01/2021 - 09/2003
9	Epilepsy (Aura) 09/2015 - 12/2006
8	Dyskinesias (Dyskinesia) 01/2020 - 07/2002
8	Tauopathies 11/2016 - 11/2005
7	Alzheimer Disease (Alzheimer's Disease) 12/2023 - 08/2002
7	Parkinsonian Disorders (Parkinsonism) 01/2022 - 09/2003
6	Multiple System Atrophy 01/2021 - 01/2010
5	Synucleinopathies 09/2022 - 07/2014
5	Sleepiness 09/2015 - 05/2002
5	Seizures (Absence Seizure) 01/2013 - 06/2008
4	Anosmia 12/2023 - 09/2015
4	Pain (Aches) 10/2011 - 08/2006
3	Movement Disorders (Movement Disorder) 12/2023 - 10/2003
3	Cognitive Dysfunction 01/2021 - 01/2009
3	Myasthenia Gravis 12/2014 - 03/2007
3	Neuroinflammatory Diseases 01/2014 - 01/2013
3	Multiple Sclerosis 10/2013 - 03/2002
3	Tremor (Tremors) 01/2010 - 09/2003
2	Prodromal Symptoms 11/2023 - 01/2023
2	Atrophy 01/2022 - 05/2002
2	Mental Disorders (Mental Disorder) 12/2017 - 02/2009
2	Epileptic Syndromes 02/2014 - 03/2011
2	Generalized Epilepsy 02/2014 - 11/2004
2	Neoplasms (Cancer) 01/2014 - 01/2013
2	Nausea 01/2014 - 10/2010
2	Partial Epilepsies (Epilepsy, Partial) 06/2013 - 05/2012
2	Autoimmune Diseases (Autoimmune Disease) 01/2013 - 03/2009
2	Dystonia (Limb Dystonia) 06/2012 - 01/2010
2	Brain Diseases (Brain Disorder) 12/2011 - 12/2002
2	Schizophrenia (Dementia Praecox) 12/2011 - 06/2011
2	Migraine Disorders (Migraine) 06/2011 - 02/2009
2	Idiopathic Generalized Epilepsy 02/2010 - 03/2008
2	Temporal Lobe Epilepsy 02/2010 - 09/2009

Drug/Important Bio-Agent (IBA)

17	Levodopa (L Dopa)FDA LinkGeneric 01/2020 - 05/2002
15	SynucleinsIBA 12/2023 - 01/2013
15	Biomarkers (Surrogate Marker)IBA 12/2023 - 01/2010
12	Dopamine Agonists (Dopamine Agonist)IBA 09/2015 - 05/2002
9	alpha-SynucleinIBA 01/2018 - 09/2005
9	rotigotine FDA Link 09/2015 - 12/2004
9	Pramipexole (Mirapex)FDA LinkGeneric 07/2014 - 01/2004
8	Anticonvulsants (Antiepileptic Drugs)IBA 09/2015 - 12/2008
8	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 05/2015 - 06/2011
7	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 12/2023 - 10/2003
6	2- carbomethoxy- 8- (3- fluoropropyl)- 3- (4- iodophenyl)tropaneIBA 01/2022 - 09/2003
6	Oxidopamine (6 Hydroxydopamine)IBA 05/2015 - 11/2003
5	Dopamine (Intropin)FDA LinkGeneric 01/2019 - 07/2004
5	AutoantibodiesIBA 10/2014 - 03/2007
5	Proteins (Proteins, Gene)FDA Link 01/2013 - 11/2003
5	Dopamine Agents (Dopaminergic Agents)IBA 01/2007 - 05/2002
4	IronIBA 11/2023 - 01/2007
4	annonacinIBA 11/2016 - 07/2007
4	Valproic Acid (Depakote)FDA LinkGeneric 10/2013 - 12/2002
4	Amyloid beta-PeptidesIBA 07/2013 - 08/2002
4	CytokinesIBA 04/2011 - 11/2003
3	tau Proteins (tau Protein)IBA 12/2023 - 11/2005
3	GhrelinIBA 12/2017 - 06/2011
3	EnzymesIBA 09/2015 - 07/2008
3	Intravenous Immunoglobulins (IVIG)FDA Link 12/2014 - 08/2002
3	AntibodiesIBA 10/2014 - 08/2002
3	Tolcapone (Tasmar)FDA Link 01/2014 - 01/2008
3	Carbamazepine (Tegretol)FDA LinkGeneric 01/2011 - 12/2008
2	Chelating AgentsIBA 11/2023 - 12/2002
2	Cholinergic Agents (Cholinergics)IBA 01/2022 - 01/2013
2	Amantadine (Aman)FDA LinkGeneric 01/2020 - 12/2006
2	epigallocatechin gallate (epigallocatechin-3-gallate)IBA 01/2019 - 04/2016
2	Glucosylceramidase (Glucocerebrosidase)IBA 01/2018 - 09/2015
2	Oxycodone (Oxycontin)FDA LinkGeneric 01/2016 - 12/2008
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 05/2015 - 12/2012
2	EpitopesIBA 10/2014 - 03/2007
2	Immunoglobulin G (IgG)IBA 10/2014 - 10/2013
2	Immunoglobulin A (IgA)IBA 10/2014 - 10/2013
2	Immunoglobulin M (IgM)IBA 10/2014 - 10/2013
2	ropinirole (Requip)FDA LinkGeneric 07/2014 - 01/2008
2	Hydroxyl RadicalIBA 01/2014 - 08/2005
2	Adenosine Triphosphate (ATP)IBA 12/2013 - 07/2007
2	NeurotoxinsIBA 12/2013 - 08/2005
2	Ferritins (Ferritin)IBA 11/2013 - 01/2007
2	AntigensIBA 01/2013 - 03/2002
2	perampanelIBA 01/2013 - 02/2012
2	alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA 01/2013 - 02/2012
2	Neuregulin-1 (Neuregulin 1)IBA 12/2012 - 06/2011
2	Levetiracetam (Keppra)FDA LinkGeneric 11/2012 - 11/2004
2	neuromelaninIBA 02/2011 - 01/2007
2	Immunoglobulin E (IgE)IBA 02/2010 - 03/2008
2	coenzyme Q10 (CoQ10)IBA 05/2008 - 07/2007
2	Pergolide (Permax)FDA Link 01/2008 - 03/2006
2	Cabergoline FDA LinkGeneric 01/2008 - 08/2003

Therapy/Procedure

23	Therapeutics 09/2023 - 05/2002
6	Transcranial Magnetic Stimulation 06/2011 - 08/2006
5	Transplantation 04/2012 - 07/2002
4	Deep Brain Stimulation 04/2016 - 07/2008
3	Transdermal Patch 10/2010 - 12/2008
3	Drug Therapy (Chemotherapy) 01/2010 - 07/2005
2	Ketogenic Diet 09/2013 - 01/2011